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KISS-002A
Kisspeptin-54 (human)
Gly-Thr-Ser-Leu-Ser-Pro-Pro-Pro-Glu-Ser-Ser-Gly-Ser-Arg-Gln-Gln-Pro-Gly-Leu-Ser-Ala-Pro-His-Ser-Arg-Gln-Ile-Pro-Ala-Pro-Gln-Gly-Ala-Val-Leu-Val-Gln-Arg-Glu-Lys-Asp-Leu-Pro-Asn-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2 Trifluoroacetate salt
Size:0.5mg
P1(RMB):1900
MW:5857.51
One letter sequence:GTSLSPPPESSGSRQQPGLSAPHSRQIPAPQGAVLVQREKDLPNYNWNSFGLRF-NH2
Molecular Formula:C258H401N79O78
Description:Kisspeptin-54, an endogenous ligand of the G protein-coupled receptor GPR54, is a key regulator of the hypothalamo-pituitary-gonadal (HPG) axis. It stimulates LH and FSH secretion. Kisspeptin-54 may represent a versatile tool for the manipulation of the HPG axis.
Literature Reference:M.L.Gottsch et al., Endocrinology, 145, 4073 (2004) S.B.Seminara and U.B.Kaiser, Endocrinology, 146, 1686 (2005) W.S.Dhillo et al., J. Clin. Endocrinol. Metab., 90, 6609 (2005) W.S.Dhillo et al., J. Clin. Endocrinol. Metab., 92, 3958 (2007)
Cas:374683-24-6
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