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        AAV2-001A
        Adeno-Associated Virus Epitope 2 (AAV2)
        Val-Pro-Gln-Tyr-Gly-Tyr-Leu-Thr-Leu
        Size:1mg
        P1(RMB):278
        MW:1053.2
        One letter sequence:VPQYGYLTL-OH
        Molecular Formula:N/A
        Description: This peptide is the CD8 T cell epitope from adeno-associated virus 2 (AAV2) capsid. Liver toxicity observed in a clinical trial of AAV2 delivered systemically to patients with hemophilia was ascribed to killing of vector-transduced hepatocytes by capsid-specific T-cells.
        Literature Reference:Murphy, S. et al. Blood (ASH Annual Meeting Abstracts), 108 (2006) Mingozzi, F. et al. Nature Medicine 10.1038/nm1549 (2007) Wang, L. et al. Therapy. 18, 185 (2007).
        Cas:N/A
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